Answer to Question #111518 in Biochemistry for Ibrahim jibrin

Question

The operation of the Embeden Meyer-hoff's pathway is manipulated at key steps to achieve its dual role. Discuss.

Answer 1

 In glycolysis there are three highly exergonic steps. These are also regulatory steps which include the enzymes hexokinase, phosphofructokinase, and pyruvate kinase.

The four regulatory enzymes are hexokinase (or glucokinase in the liver), phosphofructokinase, and pyruvate kinase. The flux through the glycolytic pathway is adjusted in response to conditions both inside and outside the cell