Isopropyl bromide's use in the synthesis of pharmaceuticals, dyes, and other organics could result in its release to the environment through various waste streams. Isopropyl bromide should have high to very high mobility in soil. Volatilization of isopropyl bromide is expected from both moist and dry soils. In water, isopropyl bromide is expected to volatilize rapidly with estimated half-lives of 3.329 hours and 4.4 days from a model environmental river and a model environmental lake, respectively. Hydrolysis is expected to be an important fate process in aquatic systems and in moist soil based on a neutral hydrolysis half-life of 2.1 days. Bioconcentration and adsorption to sediment are not expected to be important in aquatic systems. Biodegradation of isopropyl bromide is expected to be an important fate process in both soil and aquatic conditions based on a closed bottle biodegradation study. Isopropyl bromide will exist in the vapor phase in the ambient atmosphere. If released to the atmosphere, it will degrade by reaction with photochemically produced hydroxyl radicals with an estimated half-life of approximately 24 days. Removal of isopropyl bromide from the atmosphere can occur though wet deposition. Exposure to isopropyl bromide can occur through dermal contact, inhalation, and ingestion.