Answer to Question #190488 in Biochemistry for Raiko

Question #190488

Answer the ff. questions:

1. What is the fate of proteases after their role in protein digestion?

2. Why is arginine classified as an essential amino acid in humans when it is synthesized in the urea cycle?

3. How do higher organisms obtain ammonia?

Expert's answer


1) The fate of proteases after their role in protein digestion is , as protein source reaches stomach , Hcl and enzymes called

protease break it down into smaller chains of amino acids . These acids are joined together by peptides.

2)Arginine (2 amino-5-guanidinovaleric acid) is one of the 20 amino acid that are coded for a part of ribosomal protein synthesis in humans. When arginine is synthesized in the urea cycle, it not only act as a chemical intermediate in the release of nitrogenous waste, where the enzyme arginase (ARG) converts ornithine and urea allowing it (urea) to be secreted; arginine is also a structural component of many proteins and also serves as therapeutic target in a number of diseases, wound healing as well as cancer.

3)Higher organism (complex organisms) acquire ammonia in tow ways; one is through nitrogen fixation, in which nitrifying organism such a nitrobacter residing in roots nodules of legumes e.g Rhizobium, converts nitrogen gas from the atmosphere in the soil to nitrates (ammonium nitrates). Another way in which ammonia is availed to higher organisms is through decomposition process; the decomposers dissolves tissues of dead plants and animals and releases the nutrients including ammonium nitrates into soil and eventually get absorbed by plants and other organisms such as fungi.

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