Answer to Question #143267 in Chemistry for ali

Question #143267
1) How the change of shape can affect the signal transduction? Consider the addition of
long alkyl chain.

2) How the change of binding groups can affect the signal transduction? Consider the
exchange of phenyl group by cyclohexyl group.

3) How the change of position of binding group can affect the signal transduction?
Consider the constitutional isomers.
4) How the change of position of binding group can affect the signal transduction?
Consider two chiral molecules.
5) Name the main requirements for an agonist.
6) How can drug act as agonist without binding to the binding site?
7) How can drug act as antagonist without binding to the binding site?
8) What is partial agonist?
9) Explain the role of side chain for antagonist using raloxifene as an example.
1
Expert's answer
2020-11-08T12:14:17-0500
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