0.10 g glycine and 0.4 ml water taken in 5 ml conical vial. Warmed slightly to dissolve the
glycine. 0.3 rnl acetic anhydride added and stirred for about 5 min. Mixture cooled in ice
bath for 10 min. Precipitate collected by suction filtration and washed with a few ml water.
Clystais spread over a piece olfiiter papel or watch glass and air dried for i0 min. Mass and
melting point of product recorded.
Glycine dissolved after about 20 sec when watmed in gl5'cineiwater mixture'
White, needle-shaped crystals formed when reaction mixture cooled in ice.
0.14 g. of solid obtained after f,rltration and drying of product.
mp of crystals recorded as 205-207 n
Solid product possibly still slightly wet.
Conclusion: crystallized material was in fact acetanilide, based on its melting point. Not
highly pure. A second crystallization should produce a fairly pure material, but it would also
decrease the % recovery
Unfortunately, the statement of your question is a bit confusing. What do you need to be done? Please provide the details so we could help you.
Yes, each purifying step results in lowering the total product yield.
Can you explain the conclusion part. crystallized material was in fact
acetanilide, based on its melting point. Not highly pure. A second
crystallization should produce a fairly pure material, but it would
also decrease the % recovery.
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