Answer to Question #203482 in General Chemistry for sir

Question #203482

Identify chiral molecules and explain how optical isomerism influences the effects of drugs – use the drug thalidomide as an example


1
Expert's answer
2021-06-07T03:15:25-0400

Chiral molecules usually contain at least one carbon atom with four nonidentical substituents. Such a carbon atom is called a chiral center (or sometimes a stereogenic center), using organic-speak. Any molecule that contains a chiral center will be chiral (with the exception of a meso compound).


The Reality of Optical Isomerism In Thalidomide


The means that both enantiomers are formed in a roughly equal mix in the blood. So, even if a drug of only the 'R' isomer had been created, the disaster would not have been averted.



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