Answer to Question #122617 in Biology for fiso

Question #122617
The fifth C becomes U
Met Lys Leu Ser Arg Val Phe Tyr
AUGAAA CUUUCA CGCGUUUUCUAU


The third U becomes A.
Met Leu Iso Leu Thr Leu Leu Val
AUGUUGAUA CUUACA CUUCUGGUC

what will be mutated mRNA and acids of these sequences?
1
Expert's answer
2020-06-22T13:26:40-0400

1. The mRNA sequence with the mutant C:

AUGAAA CUUUCA CGCGUUUUUUAU

This mutation results in the substitution of codon UUC by codon UUU. As both codons encode the same amino acid phenylalanine (Phe), the amino acid sequence is not changed:

Met Leu Iso Leu Thr Leu Leu Val


2. If the third U becomes A, the mRNA sequence is as following:

AUGUAGAUA CUUACA CUUCUGGUC

Mutant codon UAG is a stop codon. As a result, the mRNA cannot be translated as the second triplet encodes a stop codon.


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