Answer to Question #233616 in Biology for jess

Question #233616

antigenic determinant genes are usually removed from the pathogen during generation of attenuated vaccines


1
Expert's answer
2021-09-06T17:09:04-0400

False.

Live attenuated vaccines contain whole bacteria or viruses which have been “weakened”(attenuated) so that they create a protective immune response but do not cause disease in healthy people.

The major disadvantage of attenuated vaccines is that secondary mutations can lead to reversion to virulence and can thus cause disease. There is another possibility of interference by related viruses, as is suspected in the case of oral polio vaccine in developing countries.


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