HIV infects so-called CD4+ T cells (also called T helper cells), macrophages and dendritic cells. The most damage is done to the T helper cells. After several years of infection, number of this cells is decreased greatly, what leads to immunodeficiency (in fact, this is the only significant damage that is caused by HIV/AIDS). The weak immune system cannot resist to widespread infections (like fungal diseases) and the organism finally dies because of some simple illness.
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