Answer to Question #64977 in Molecular Biology for Sanjukta Ghosh
Why are mutant tumour-suppressoor genes and oncogenes generally recessive and dominant respectively?
In contrary, cellular oncogenes (proto-oncogenes) are silent in the absence of the pattern of both internal and external stimuli. This means that cancerogenesis requires overexpression of proto-oncogenes. And activating mutations are generally dominant.
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