58 622
Assignments Done
Successfully Done
In March 2018
Your physics homework can be a real challenge, and the due date can be really close — feel free to use our assistance and get the desired result.
Be sure that math assignments completed by our experts will be error-free and done according to your instructions specified in the submitted order form.
Our experts will gladly share their knowledge and help you with programming homework. Keep up with the world’s newest programming trends.

Answer on Molecular Biology Question for falastin

Question #34889
If a patient had a mutation in the insulin receptor which caused them to make TOO much insulin receptor, which would you expect?
Expert's answer
Anunexpected observation was the ability of mitogens, such as concanavalin A and Epstein-Barr virus, to increase expression of insulin receptors (IRs) in lymphocytes. Moreover, human lymphocyte-derived malignant cells, such as the IM-9 cells (B-type lymphoblasts derived from a subject with multiple myeloma), are abundantly endowed with high-affinity IRs. IR up-regulation in these cells has no major effect on cell metabolism, but coincides with the development of increased sensitivity to the nonmetabolic effects of insulin. A role for IR in tumor progression was suggested by studies indicating that IR is overexpressed in several tumors, including breast, colon, lung, ovary, and thyroid carcinomas.

Need a fast expert's response?

Submit order

and get a quick answer at the best price

for any assignment or question with DETAILED EXPLANATIONS!


No comments. Be first!

Leave a comment

Ask Your question