Answer to Question #32110 in Molecular Biology for Susan
2. The F1 portion of the ATP synthase is above the membrane, inside the matrix of the mitochondria.
The FO region of ATP synthase is a proton pore that is embedded in the mitochondrial membrane. It consists of three main subunits A,
B, and C, and (in humans) six additional subunits, d, e, f, g, F6, and 8.
Subunit A- Human Gene ATP6, B- ATP5F1, C- ATP5G1, ATP5G2, ATP5G3.
F1-ATP synthase subunits:
Subunit alpha - Human Gene ATP5A1, ATPAF2;
beta - ATP5B, ATPAF1, C16orf7;
gamma - ATP5C1;
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