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Answer to Question #23207 in Molecular Biology for Karim

Question #23207
What are local and non-local interaction in protein folding?
Expert's answer
Here are two types of non-covalent interaction in proteins: local and non-local, so defined in terms of the distance in the sequence between the interacting residues. Importantly, they are geometrically different; local interactions participate in defining secondary structure while non-local interactions are involved in defining the tertiary structure.

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