Answer to Question #214496 in Molecular Biology for Moe

Question #214496

2.2) Explain how the DNA lagging strand is synthesised especially when DNA polymerase adds nucleotides only to the 3´ end. Include a fully labelled diagram in your answer to show how this strand is synthesised


1
Expert's answer
2021-07-26T17:07:03-0400

On the lagging strand, DNA synthesis restarts many times as the helix unwinds, resulting in many short fragments called “Okazaki fragments.” DNA ligase joins the Okazaki fragments together into a single DNA molecule.DNA polymerase III extends the primers, adding on to the 3' end, to make the bulk of the new DNA.


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