Answer to Question #183961 in Molecular Biology for MIR MUSTAFFA

Question #183961

) When so much damage occurs in DNA that during excision reparation the cell does not have time to completely eliminate them. As a result, after replication of this DNA the daughter chain has “gaps” that are formed at the site of damage of the mother DNA chain,.

1. What type of reparation corrects such damage?

2. What are the molecular mechanisms the cause of this disorder?

Expert's answer

1. Recombination repair

2. Molecular mechanism cause of this disorder occurs when damaged nucleotides are cut out of the growing strand such that a lesion is created, the final remaining strand is used as a template for synthesis a complimentary strand often past the lesion leaving a gap at the lesion site.

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