The main difference between eukaryotic genes and prokaryotic genes is that most of eukaryotic genes have an intermittent structure and consist of coding regions - exons and non-coding inserts - introns.
The translation mechanism in eukaryotes is not fundamentally different from prokaryotic. However, a significantly larger number of protein translation factors is involved in the maintenance of this stage of protein synthesis of eukaryotes than in bacteria.
Eukaryotic genomes contain the specialized terminal sections of chromosomes - telomeres.
In prokaryotes, only one type of regulation is possible - at the level of transcription using the operon system while eukaryotic genome has multilevel nature of the regulation of the action of genes.