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Answer to Question #55764 in Microbiology for tony

Question #55764
Would you expect to use amphotericin B against a bacterial infection? A fungal infection? Offer a reason why amphotericin B has severe side effects in humans.
Expert's answer
Amphotericin B is an antifungal drug. It is specific only to fungal infections and cannot be used against a bacterial infection. Amphotericin B forms pores in fungal cell membranes after binding ergosterol and causes their death. At the same time, this drug forms pores in host cells membranes causing their destruction. This is a reason why amphotericin B is toxic for humans and causes severe side effects.

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