The goal of this course is to give students a basic grasp of the immune response to infection and the roles of innate and adaptive immunity. The course lays the groundwork for later pathogen biology courses.
In introduction to the course under immunity there is need to or we explained the immune system's tissues, cells, and molecular components, as well as the importance of primary immunodeficiency in the context of infection.
Under pathogen detection, Complement and Interferon responses we describe key features of the innate and adaptive immune responses, examine the relative importance of specific immune response arms in the light of clinically relevant illnesses, and how this affects vaccine development and clinical management of immuno-compromised patients, for example. Antibody vs. cell-mediated immunity, for example. Participants will use examples from professional practice and/or self-directed research to illustrate their points.
Under T lymphocyte responses to infection, Antigen presentation to T cells ,the development and functions of T cell subsets and Define and discussion of the phases of an immune response. Critique and discuss opposing views/models on how the immune system functions.
discussion of the features of vaccine types formulation and types of immune response induced. Discuss factors that can undermine the success of a specific vaccine. For example, formulation/ choice of adjuvant. programs of vaccination and types of immunity attained that is for example herd immunity a nd discussion of the relative merits of vaccination use over administration of therapeutics. Is it better to treat or is vaccination always preferable?
At the end of the course we took a research portfolio that includes critical evaluation of research papers, clinical case studies, and professional experience, if applicable produce a critical written evaluation on the course material's impact on the professional conduct.