Answer to Question #130827 in Microbiology for Ali hassan

Question #130827
Studies on bacteria capable of degrading antibiotics. Write down practical with apparatus and procedure.
1
Expert's answer
2020-08-28T04:38:06-0400

The three fundamental mechanisms of antimicrobial resistance are (1) enzymatic degradation of antibacterial drugs, (2) alteration of bacterial proteins that are antimicrobial targets, and (3) changes in membrane permeability to antibiotics. Antibiotic resistance can be either plasmid mediated or maintained on the bacterial chromosome. The most important mechanism of resistance to the penicillins and cephalosporins is antibiotic hydrolysis mediated by the bacterial enzyme β-lactamase. The studies of resistance can be done through a sensitivity test using bacteria cultures and sensitivity discs.


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