The influenza virus is the family of Orthomyxoviridae that houses multiple RNA segments that have negative polarity. Therefore, the replication and the transcription of the influenza genome take place within the nucleus of the cells that are infected. The influenza virus is rough and cylindrical with the outer layer being lipid membrane. On the other hand, T4 bacteriophage is categorized under Myoviridae family since it contains a tail that is contractile. Therefore, the head, the tail and the fibers of the tail are gathered independently prior to joining together to give a phase that is mature.