Answer to Question #103349 in Human Anatomy and Physiology for Nibedita Rudra

Question #103349
Compare the oxygen dissociation curves of haemoglobin and myoglobin.
1
Expert's answer
2020-02-19T05:49:40-0500

The oxygen dissociation curve for hemoglobin has a sigmoid shape because of the co-operative binding of oxygen to the 4 polypeptide chains. On the other hand, Myoglobin is made up of a single polypeptide with only one heme group and hence is not capable of cooperative binding. Thus the oxygen dissociation curve is not sigmoid but it is a hyperbola.


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