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Answer to Question #70241 in Genetics for Nikhil

Question #70241
Can lethal genes be considered as a part of Pleiotropic genes or are they two different things? Eg: Sickle cell anaemia is an example of pleotropic gene but it can also mean presence of lethal genes in homozygous recessive state and semi lethal in heterozygous state?
Expert's answer
Yes, lethal genes can be considered as a part of pleiotropic genes. Second question is not a question actually, but anyway, yes, sickle cell anemia is good example of disease caused by pleotropic gene with lethal effect.

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