Answer on Genetics Question for ekam
known as “Met” and “Val”. People who are homozygous for the Met allele can contract
“variant CJD”, the fatal human form of mad cow disease associated with the consumption of
In Denmark, a survey of 352 individuals found that 131 were homozygous for Met, 168 were
heterozygous, and 53 were homozygous for Val. Is the PRNP gene in Hardy-Weinberg
equilibrium? Show your calculations.
The frequency of allele for Val is (2*53+168)/2*352=0.39
According to the calculated frequencies, the number of individuals, who are homozygous for Met, should be: 0.61^2 *352=131
In the same way, the expected number of heterozygous individuals is 2*0.61*0.39*352=168
Similarly, the expected number of individuals who are homozygous for Val is: 0.39^2*352=53
Thus, the PRNP gene is in Hardy-Weinberg equilibrium
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