Answer to Question #155766 in Genetics for Virat

Question

3. The pediatrician of the maternity hospital examined the child and found that the anus was missing. The child was urgently sent to the pediatric surgical department.

Questions:

1. What cellular mechanism of ontogenesis is likely to be disturbed?

2. Name, are there any other mechanisms?

Answer 1

1. Gastrulation and formation of blastopore ( primary mouth in Deuterostomia) - then it becomes anus. If some molecular mechanisms of gastrulation are disturbed, there will be disorders with it
2. There may be some other postgastrula mechanisms, that will disrupt or destroy blastopore - leading to the same result or abnormalities which can leave anus as primary mouth