Answer to Question #84892 in Cell Biology for shetal sajeev

Question

Describe the methods for the separation of macromolecules based on their
molecular size and solubility.

Answer 1

Macromolecules and microparticles can be separated in the following ways:

- Centrifugation - this is the separation of heterogeneous systems into fractions by density using centrifugal forces.

- Filtration - the process of separating solids from liquids or gases by passing them through a filter.

- Electrophoresis - this is the process of directed motion of particles dispersed in a liquid in a constant electric field.

- Chromatography - this is a dynamic method of separation and determination of substances based on multiple distribution of components between two phases – mobile and non-mobile.