Two 10- and 11-years old boys infected with a Respiratory syncytial virus (RSV) and consulted a physician. Their mother states that a high fever occurred during the last 24 hours. The physician observed that both had a viral illness and laboratory test positive for RSV infection, and the mother told the doctor both received a subunit vaccine against RSV a year ago. For the first son, fever disappeared the next day but not for the second son, have high fever and breathing problems even after five days. Write a detailed explanation and schematic diagram/graph for the following questions: What are the immunological reactions that might happen during the vaccination in both first and second children? Why the boys got RSV infection even after vaccination? Why fever disappears for the first why not to the second? What kind of immunological response might happen to the first and second children after infection?
The first response to a vaccine is alike to that of the primary retort upon the first contact with a pathogen, thus limited and slow. Succeeding doses of the same vaccine perform to increase this response consequential in the formation of long-lasting antibodies and immunological cells, as it would succeed consequent infections in the case of the two boys.
Each boy carries a diverse repertoire of lymphocytes replicating their exceptional display of gene reorganizations.
The viral infection load was much in the second boy compared to the first boy. Therefore, fever disappeared in the first boy tan in the second boy.
Lastly, the immunological response is the capacity of the immune system to react extra fast and efficiently to pathogens that have been met previously and reflect the precarious of a cleanly extended populace of antigen-particular lymphocytes. These secondary responses depend on the sum of acquaintances to antigen. It likewise differs from primary responses. The process is clear in two boys regarding the antibody response, where the physiognomies of antibodies formed in secondary and following responses are different from those created in the primary retort to the similar antigen.