Answer to Question #161570 in Cell Biology for Virat

Question

Populate the table using the OMIM database. OMIM (Online Mendelian Inheritance in Man) is a medical database that collects information about known diseases with a genetic component and the genes responsible for their development. This database provides a bibliography for future research, a toolkit for genomic analysis of a registered gene, and is used in the medical literature to provide a single index for genetic diseases.

No Name of Gene Localisation of Gene Determine the type of mutation Inheritance type Name of the disease

1 TYR

2 FBN1

3 HBB

4 HTT

5 STS

Answer 1

TYR- Elimination of tyrosinase activity causing oculocutanous albinism.

FBN1- Autosomal dominance causing Marfan syndrome.

HBB- Alterations of beta-globin protein causing sickle cell anaemia.

HTT- Compound heterozygous mutation in HTT gene causing huntington disease.

STS- Deletion of STS gene causes x-linked ichthyosis.