Answer to Question #144494 in Cell Biology for Emma Million

Question #144494
What differences did you notice between the point mutation and the frameshift mutations?
Expert's answer

Differences between Point Mutations and Frameshift Mutations

There are five main differences between point mutations and Frameshift Mutations. One of the differences is that point mutations occur when one base pair is replaced by another, while frameshift mutation takes place when there is deletion or insertion involving the base pairs and the DNA structure.

The second difference is that point mutations result from the alterations within a single nucleotide, while frameshift mutation happens as a result of the alterations in several nucleotides.

The third difference is that the point mutation results in a change of the gene structure due to the substitution of another pair of the base, whereas frameshift mutation changes the number of nucleotides as a result of deletions or insertions of the nucleotides.

The fourth difference is that transversions and transitions are considered to be the point mutation types, while deletions and insertions are perceived to be frameshift mutation types.

The last difference is that point mutations result in sickle cell anemia due to the gene structure changes, while frameshift mutation leads to Tay-Sachs disease due to the change in the number of base pairs within the gene DNA structure.

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