Question #21392

What are the application of binomial distribution in Bioinformatics

Expert's answer

The examples of uses of the binomial distribution in bioinformatics include:

1. calculating the probability that a certain position in a DNA sequence is or is not the beginning of a restriction site

2. calculating the probability of a certain number of A alleles being seen in a population (at a locus with two alleles (A,a)) at generation x+1, given the frequency of A alleles in the population at generation x

3. modeling the number of C/G versus A/T bases in n-bp chunks of yeast chromosomes using a binomial distribution.

1. calculating the probability that a certain position in a DNA sequence is or is not the beginning of a restriction site

2. calculating the probability of a certain number of A alleles being seen in a population (at a locus with two alleles (A,a)) at generation x+1, given the frequency of A alleles in the population at generation x

3. modeling the number of C/G versus A/T bases in n-bp chunks of yeast chromosomes using a binomial distribution.

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