Answer to Question #199604 in Bioinformatics for Ayesha Arshad

Question #199604

What are different nucleotide and protein databases? Describe the salient features of each with emphasis on pros and cons. 

1
Expert's answer
2021-05-31T03:27:02-0400

Different nucleotide are; adenine (A), thymine (T), guanine (G), and cytosine (C). These nucleotide have three features: (1) a nitrogenous base, (2) a pentose, and (3) a phosphate.


A protein database is one or more datasets about proteins, which could include a protein's amino acid sequence, conformation, structure, and features such as active sites.

Protein databases are categorized into:

  • Sequence databases: GenBank, European Nucleotide Archive and DNA Data Bank of Japan.
  • Secondary databases: UniProt, database of protein sequences grouping together Swiss-Prot, TrEMBL and Protein Information Resource.
  • Other databases: Protein Data Bank, Ensembl and InterPro.

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