Answer to Question #154909 in Bioinformatics for vaibhav

Question

Two proteins have 20 % sequence identity. Is this likely to be significant? What other simple piece of information do you need to answer this question properly?

Answer 1

This is very small percentage of identity for some conclusions about shared or common origin from one protein families. Besides it, in bioinformatics we need not only percentage of identity for result, but e-value, query cover and total match score.