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Answer on Biochemistry Question for Sanjukta Ghosh

Question #57334
What does E stand for in E-biotin,prosthetic group of enzyme pyruvate caboxylase?
Expert's answer
Pyruvate carboxylase (PC; EC, a member of the biotindependent enzyme family, catalyses the ATP-dependent carboxylation of pyruvate to oxaloacetate. This enzyme contains the prosthetic group biotin, which is covalently bound to the ε-amino group of a specific lysine residue. The biotin carboxylase enzymes – E-biotin, where E denotes enzyme.
PC has been found in a wide variety of prokaryotes and eukaryotes. In mammals, PC plays a crucial role in gluconeogenesis and lipogenesis, in the biosynthesis of neurotransmitter substances, and in glucoseinduced insulin secretion by pancreatic islets.

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Assignment Expert
27.01.2016 12:02

Dear Sanjukta Ghosh. You are welcome. We are glad to be helpful. If you really liked our services please press like button beside answer field. Thank you!

Sanjukta Ghosh
26.01.2016 13:22

Thank you.

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