Answer to Question #5706 in Biochemistry for SHAGUFTA PARVEEN

Question

EXPLAIN HOW ENZYMES LOWER THE ACTIVATION ENERGY OF A REACTION

Answer 1

The activation energy of a reaction is lowed with 2 ways:
1) Entropic
catalysis: an enzyme binds 2 substrates in the special orientation against an
active center of the enzyme.
2) Enthalpy catalysis: Before the covalent
bonds rebuilding of the substrates it appears an intermediate-compound, to which
the enzymes is more related. It provides lower activation energy.