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Answer to Question #33545 in Biochemistry for Russinariti

Question #33545
When palmitate labeled with 14C at every even-numbered carbon is added to liver homogenate, where does the radiolabeled appear in mevalonate?
Expert's answer
Eachcarbon of mevalonate will be labeled, taking into account beta-oxidation of 14C-palmitateto the molecules of Acetyl-KoA. Condensation of three acetate units is necessary to form a six-carbon intermediate, mevalonate.

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