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Answer to Question #273476 in Biochemistry for nk123
Question #273476
What is the connection between glucagon and urea cycle?
Expert's answer
Glucagon receptor signalling increases urea cycle activity by activating the cAMP-protein kinase A (PKA)-cAMP response element-binding (CREB) protein-pathway, resulting in transcription of urea cycle enzymes and amino acid transporters, the latter serving to increase substrate availability
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