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Answer to Question #248367 in Biochemistry for Mpho

Question #248367

how does nitric acid lead to mistakes during DNA replication


1
Expert's answer
2021-10-11T03:05:02-0400

Hypoxanthine and 8-azaadenine are formed when nitric oxide interacts with hydroxyl radical-induced adenine radicals. Nitric oxide radiosensitization of cells promotes cellular DNA double strand breaks. DNA damage caused by nitric oxide may result in replication-induced double strand breaks.


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