Answer to Question #238776 in Biochemistry for Sam

Question

How does Haworth Projection Formula explain the cyclic form of a monosaccharide? You may draw your explanation.

Answer 1

monosaccharide often switches from the acyclic (open-chain) form to a cyclic form, through a nucleophilic addition reaction between the carbonyl group and one of the hydroxyls of the same molecule. The reaction creates a ring of carbon atoms closed by one bridging oxygen atom.