Answer to Question #210833 in Biochemistry for Maria

Question #210833

I learnt that all the enzymes of the Krebs cycle are inside the mitochondrial matrix except for the succinate dehydrogenase . can u please explain me why? Thank you so much

PS U can give me a complicated answer if it is needed; i will search for all the information to understand it


1
Expert's answer
2021-06-28T14:25:01-0400

Majorly, all enzymes of TCA cycle are present in mitochondrial matrix except succinate dehydrogenase. 

Notably, succinate dehydrogenase is tightly bound to the inner mitochondrial membrane in eukaryotes and  to the plasma membrane in prokaryotes. It has three different iron-sulfur clusters and one covalently bound FAD. Before entering ETS in mitochondria, electrons pass from succinate through the FAD and iron-sulfur centers.


Need a fast expert's response?

Submit order

and get a quick answer at the best price

for any assignment or question with DETAILED EXPLANATIONS!

Comments

No comments. Be the first!

Leave a comment

Ask Your question

LATEST TUTORIALS
New on Blog
APPROVED BY CLIENTS