Answer to Question #198367 in Biochemistry for aqsa urooj

Question #198367

Almost no metabolic reaction is able to occur without the help of an enzyme. Explain how the structure of an allosteric enzyme and substrate function to control a metabolic pathway. Include a specific example in your answer.

1
Expert's answer
2021-05-26T22:22:01-0400
  • In noncompetitive inhibition (also known as allosteric inhibition), an inhibitor binds to an allosteric site; the substrate can still bind to the enzyme, but the enzyme is no longer in optimal position to catalyze the reaction.
  • Allosteric inhibitors induce a conformational change that changes the shape of the active site and reduces the affinity of the enzyme’s active site for its substrate.

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