What are the possible causes of macrocyosis and how can be corrected?
Common causes of macrocytosis include:Vitamin B-12 deficiency Folate deficiency Liver disease AlcoholismHypothyroidismA side effect of certain medications, such as those used to treat cancer, seizures and autoimmune disorders Increased red blood cell production by the bone marrow (regeneration) to correct anemia, for example, after blood loss. Treatment of macrocytosis, if needed, is directed at the underlying cause. In the case of vitamin B-12 or folate deficiency, for instance, treatment may include diet modification and dietary supplements or injections. If macrocytosis is caused by severe anemia, a blood transfusion might be necessary.