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Which of the following enzyme can act as a polymerase as well as exonuclease?

a. RNA polymerase I c. DNA polymerase I


b. RNA polymerase III d. DNA polymerase III


Identify the F1 generation from a colourblind father and a mother who is homozygous for colour vision.



Certain human conditions result in the change in DNA sequence.  The following is a segment of the template strand of an open reading frame of a functional gene. Determine the amino acid sequence of the polypeptide fragment


How does replica plating demonstrate that muta- tions to antibiotic resistance can arise even in cells that have never been exposed to the antibiotic?

What is the purpose of the liver extract in the Ames test for chemical mutagens?

What is “mismatched” in the process of mismatch repair?

What is “loss of heterozygosity,” and how is this phenomenon related to the progression of some types of cancer?

What is apoptosis, and what role does it play in preserving the integrity of the genome of a multi- cellular organism?

What is a cell-cycle checkpoint? Which check- points are emphasized in this chapter, and what does each “check” for?

What would happen if an electrolyte solution was not used to make the gel for gel electrophoresis?


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