The passage is important, particularly to the ministry of health. The information from the primary source, such as world health organization and centre for disease and control prevention, describes the effort needed to create vaccines for the outbreak of tropical diseases. The reports also show how much research must be conducted for diseases uncertainties and prepare for the possible best solutions. Therefore, the information seems credible because the CDC director himself had faced the media by telling how the researchers need to improve their research concept. Because bad flu has become the main issue to be addressed, this article explores the manufacturing time of vaccine based on its recurrent outbreak every new season. However, the research on getting the proper vaccines for recurrent bad flu outbreak is not comprehensive due to variant strains that were not detected until march, an incidence which led to large numbers of diseases cases before September.