Answer to Question #24495 in Organic Chemistry for bhavya
How to convert aniline to methylamine?
Methylamine synthesis can be carried out using the following conversion:
At the first stage the methylation of aniline on the nitrogen atom:
Ph-NH2 + CH3I = Ph-NH-CH3 + HI with K2CO3
CH3I dropwise within one hour in an ice bath.
After the dropwise addition, the mixture is stirred at room temperature for about 24 hours.
The second stage - the nucleophilic substitution of a good leaving group strong nucleophile:
Ph-NH-CH3 + CH3OH = Ph-O-CH3 + CH3-NH2