Answer to Question #51596 in Other Biology for Sumit

Question #51596
Explain why the Red Blood Cells of an individual are not normally destroyed as a result of innocent bystander lysis by complements? When complement will cause lysis of an individual's own RBC?
1
Expert's answer
2015-03-27T10:58:32-0400
Normally, the surface of RBC contains the markers - protein inhibitors of complement system, such as CD59.
When an individual organism acquires hypersensitivity its antibodies direct against antigens of the own RBC. The resulting Ag-Ab complexes activate complement, leading to cell lysis.

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