Answer to Question #76520 in Cell Biology for Madhu
What about the polarity of microtubules in interphase cell, nerve cell, dividing cell and ciliated cell
A microtubule refers to as polymer of globular tubulin subunits, that have been arranged in a cylindrical manner. Microtubule emerges from microtubule-organizing center (MTOC. The (MTOC) helps in organizing the Celia cell that is responsible for separating the chromosome during the cell division process
Centrosomes are responsible for the movement of the microtubules. During cell division, the centrosome normally moves to the opposite ends of the main cell as it nucleate microtubules to facilitate the formation of the mitotic/meiotic spindle.
During the interphase the microtubules are attached at the MTOC by their minus ends, while their positive ends persist to develop into the cell periphery. The polarity of the microtubules is vital for cellular transportation, as the motor proteins kinesin and dynein characteristically move preferentially in the "positive" and in a negative direction in that order, along a microtubule, permitting vesicles to go to or from the endoplasmic reticulum and Golgi apparatus