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Answer to Question #76520 in Cell Biology for Madhu

Question #76520
What about the polarity of microtubules in interphase cell, nerve cell, dividing cell and ciliated cell
Expert's answer
A microtubule refers to as polymer of globular tubulin subunits, that
have been arranged in a cylindrical manner. Microtubule emerges from
microtubule-organizing center (MTOC. The (MTOC) helps in organizing
the Celia cell that is responsible for separating the chromosome
during the cell division process

Centrosomes are responsible for the movement of the microtubules.
During cell division, the centrosome normally moves to the opposite
ends of the main cell as it nucleate microtubules to facilitate the
formation of the mitotic/meiotic spindle.

During the interphase the microtubules are attached at the MTOC by
their minus ends, while their positive ends persist to develop into
the cell periphery. The polarity of the microtubules is vital for
cellular transportation, as the motor proteins kinesin and dynein
characteristically move preferentially in the "positive" and in a
negative direction in that order, along a microtubule, permitting
vesicles to go to or from the endoplasmic reticulum and Golgi
apparatus

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