Answer to Question #214300 in Cell Biology for Moe

Question #214300

1.6) Discuss Mitchell’s chemiosmotic hypothesis of ATP generation in mitochondria (discuss the roles of the electron transport chain, proton gradient and ATP synthase complex).


1
Expert's answer
2021-07-12T17:04:04-0400

The chemiosmotic hypothesis was proposed by Peter Mitchell. This hypothesis stated that a proton-motive force was responsible for driving the synthesis of ATP. In this hypothesis, protons would be pumped across the inner mitochondrial membrane as electrons went through the electron transfer chain.

The proton gradient produced by proton pumping during the electron transport chain is used to synthesize ATP. Protons flow down their concentration gradient into the matrix through the membrane protein ATP synthase, causing it to spin (like a water wheel) and catalyze conversion of ADP to ATP.


Need a fast expert's response?

Submit order

and get a quick answer at the best price

for any assignment or question with DETAILED EXPLANATIONS!

Comments

No comments. Be the first!

Leave a comment

LATEST TUTORIALS
New on Blog
APPROVED BY CLIENTS