Answer to Question #179472 in Biochemistry for Kim

Question #179472

What factors influence the metabolic rate of citrate in the mitochondria?

Expert's answer


metabolic rate of citrate


The estimated mean total citrate administered via blood and blood products was calculated as 43.2±34.19 mg/kilogram/day.

"\\bull" In non-massive and frequent blood transfusions, the elevated carbon dioxide output has been shown to occur.

"\\bull" Due to citrate metabolism causes intracellular acidosis.


Citrate Provides a Bridge Between Carbohydrate and Fatty Acid


Citrate metabolism plays an important role in many food fermentations involving lactic acid bacteria.

"\\bull" Since citrate is a. highly oxidized substrate, no reducing equivalents are produced during its degradation,

"\\bull" resulting in the formation of metabolic end products other than lactic acid.

"\\bull" Citrate metabolism in resting cells of Lactococcus lactis IL1403(pFL3) results in the formation of two end products from the intermediate pyruvate, acetoin and acetate 

"\\bull" Pyruvate is formed from citrate following uptake by the transporter CitP through the subsequent actions of citrate lyase and oxaloacetate decarboxylase. 

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